The anatomical characteristics of the human body cause it to function in a crisscross manner. The arm-and-shoulder mechanism on one side links diagonally through the torso mechanism to the hip-and-leg mechanism on the opposite side.
Think about what you're doing while walking, running, punching, throwing, and batting. Such cross-body linkages are foundational to human functioning and a big part of athletic movement.
One type of cross-body movement involves rotational core exercises, such as weight-plate chops shown here.
They're one of the most difficult muscle groups to develop, but the cure to your underdeveloped hamstrings might lie in the answer to this question: "Which way do you point your toes during a leg curl?"