The Hammer Strength unilateral supinated-grip pulldown is one of my favorite machines. It's nearly impossible to duplicate with free weights what this machine can do.
Several training methods work great on this machine, like maximum tension alternating pulls (hold one side isometrically in the contracted position at the bottom while the other side is moving). It also works great with bands for added accommodating resistance.
Step back with one leg. As you come back up, lift the dumbbell with the thigh: flex your hip and raise your knee just above a 90-degree angle with the floor.