Muscles have the lowest potential to generate force when they're either fully elongated (stretched) or fully shortened (contracted). They generate the highest possible tension in the middle – halfway through the range of motion. Another reason to focus on the mid-range is because it's the position where maximal loading of the biceps occurs.
We can use that info to make the classic 21's method for biceps even better. Try this:
Perform this protocol using two sets of dumbbells. Begin with the lighter set and perform the first exercise, then switch to a pair that's 5 pounds heavier and perform the other two exercises. For example, start with 20-pound dumbbells, then switch to 25-pound dumbbells.
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